Packers 2022 schedule release: Top 5 must-see matchups

4. Packers at Bills

A huge test for the Packers. It will be fascinating to see where this is slotted into the schedule. An early-season challenge for Matt LaFleur’s team? A game saved for primetime in December?

No matter when it’s played, this might be the toughest game on the entire schedule for Green Bay.

The Buffalo Bills enter the 2022 season among the strongest Super Bowl contenders in the league. They have become a powerhouse in the AFC with a dominant roster on both sides of the ball.

ESPN’s Mike Clay graded every roster in the NFL following the 2022 NFL Draft. Sharing top spot with the highest grade? The Packers and Bills. Clay has Buffalo’s offense ranked fifth in the NFL and its defense third.

Road games in Buffalo are always challenging. The Packers’ last trip there didn’t end well. The Bills handed the Packers a 21-13 loss in Week 15 of the 2014 season.

This is a very different Bills team. Back in 2014, they went 9-7. Now they may finish with the best record in football.

It should make for a fascinating matchup.

Great offenses. Elite quarterbacks. Defenses loaded with talent. All the ingredients of an incredible game. Maybe even a Super Bowl preview.

Arguably Green Bay’s toughest test of the season will come at Highmark Stadium.